| A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma | Children's Oncology Group | COG-ALTE21C1 | Recruiting | Screening/Early Detection |
| A Study of miRNA 371 in Patients With Germ Cell Tumors | SWOG Cancer Research Network | SWOG-S1823 | Recruiting | Other |
| A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients | Children's Oncology Group | COG-ACCL1932 | Not yet recruiting | Cancer Prevention |
| A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer | NRG Oncology | NRG-CC008 | Recruiting | Cancer Prevention |
| A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia | Children's Oncology Group | COG-ALTE22C1 | Recruiting | Other |
| A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors | Children's Oncology Group | COG-ACCL2031 | Recruiting | Supportive Care/Symptom Management/PROs |
| An Internet-based Program to Help Cancer Survivors Manage Pain | Wake Forest University Health Sciences | WF-1901 | Recruiting | Supportive Care/Symptom Management/PROs |
| An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors, DiRECT Study | University of Rochester NCORP Research Base | URCC-21038 | Recruiting | Other |
| An Observational Research Study to Uncover Subtypes of Cancer Cachexia, LOTUS-CC Study | University of Rochester NCORP Research Base | URCC-22063 | Recruiting | Other |
| An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer | St. Jude Children's Research Hospital | SENSURV | Recruiting | Other |
| Assessment of Cognitive Function in Breast Cancer and Lymphoma Patients Receiving Chemotherapy | University of Rochester NCORP Research Base | URCC-10055 | Enrolling by invitation | Supportive Care/Symptom Management/PROs |
| Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma | Children's Oncology Group | ANBL00B1 | Recruiting | Other |
| Bupropion in Reducing Cancer Related Fatigue in Stage I-III Breast Cancer Survivors | University of Rochester NCORP Research Base | URCC-18007 | Recruiting | Supportive Care/Symptom Management/PROs |
| Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors | NRG Oncology | NRG-CC011 | Recruiting | Other |
| Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection | Alliance for Clinical Trials in Oncology | A212102 | Recruiting | Screening/Early Detection |
| Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Chemotherapy | University of Rochester NCORP Research Base | URCC-19185 | Recruiting | Supportive Care/Symptom Management/PROs |
| Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy | SWOG Cancer Research Network | SWOG-S2205 | Recruiting | Supportive Care/Symptom Management/PROs |
| Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy | Wake Forest University Health Sciences | WF-2201 | Recruiting | Supportive Care/Symptom Management/PROs |
| Comparing Two Methods to Follow Patients With Pancreatic Cysts | ECOG-ACRIN Cancer Research Group | ECOG-ACRIN-EA2185 | Recruiting | Supportive Care/Symptom Management/PROs |
| Cost Communication and Financial Navigation in Cancer Patients (COSTCOM) | ECOG-ACRIN Cancer Research Group | ECOG-ACRIN-EAQ222CD | Recruiting | Cancer Care Delivery Research (CCDR) |
| Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial | Wake Forest University Health Sciences | WF-2202 | Recruiting | Supportive Care/Symptom Management/PROs |
| Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer | ECOG-ACRIN Cancer Research Group | ECOG-ACRIN-EA1151 | Recruiting | Screening/Early Detection |
| Does the Use of a Genomic Tumor Board Increase the Number of Patients Who Receive Genome-Informed Treatment | SWOG Cancer Research Network | SWOG-S2108CD | Recruiting | Cancer Care Delivery Research (CCDR) |
| Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer | Alliance for Clinical Trials in Oncology | A221805 | Recruiting | Supportive Care/Symptom Management/PROs |
| Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment | Children's Oncology Group | COG-ALTE11C2 | Recruiting | Other |
| Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors | ECOG-ACRIN Cancer Research Group | ECOG-ACRIN-EAQ211 | Recruiting | Other |
| Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer | Children's Oncology Group | COG-ACCL21C2 | Recruiting | Other |
| Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses | SWOG Cancer Research Network | SWOG-S1912CD | Recruiting | Cancer Care Delivery Research (CCDR) |
| Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II) | Alliance for Clinical Trials in Oncology | A222101 | Recruiting | Supportive Care/Symptom Management/PROs |
| Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps | NRG Oncology | NRG-CC005 | Recruiting | Other |
| Geriatric Evaluation and Management With Survivorship Health Education (GEMS) for Older Survivors of Cancer | University of Rochester NCORP Research Base | URCC-19178 | Recruiting | Supportive Care/Symptom Management/PROs |
| High-Dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients | University of Rochester NCORP Research Base | URCC-22053 | Recruiting | Supportive Care/Symptom Management/PROs |
| Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors | SWOG Cancer Research Network | SWOG-S2013 | Recruiting | Other |
| Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer | NRG Oncology | NRG-CC010 | Recruiting | Supportive Care/Symptom Management/PROs |
| Implementation and Effectiveness Trial of HN-STAR | Wake Forest University Health Sciences | WF-1805CD | Recruiting | Cancer Care Delivery Research (CCDR) |
| Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials | Eastern Cooperative Oncology Group | ECOG-ACRIN-EAQ202 | Recruiting | Other |
| Improving Patient-Centered Communication in Breast Cancer Through Patient and Provider Interventions | Alliance for Clinical Trials in Oncology | A231901CD | Recruiting | Cancer Care Delivery Research (CCDR) |
| Learning Collaborative Vs Technical Assistance in Delivering a Palliative Care Program to Patients With Advanced Cancer | University of Rochester NCORP Research Base | URCC-18110CD | Enrolling by invitation | Cancer Care Delivery Research (CCDR) |
| Making Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE) | SWOG Cancer Research Network | SWOG-S1904 | Recruiting | Cancer Prevention |
| Mobile Health for Adherence in Breast Cancer Patients | ECOG-ACRIN Cancer Research Group | ECOG-ACRIN-EAQ221CD | Recruiting | Cancer Care Delivery Research (CCDR) |
| Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study | SWOG Cancer Research Network | SWOG-S2010 | Recruiting | Supportive Care/Symptom Management/PROs |
| Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer | Wake Forest University Health Sciences | WF-1806 | Recruiting | Supportive Care/Symptom Management/PROs |
| National Cancer Institute "Cancer Moonshot Biobank" | National Cancer Institute (NCI) | NCI-2020-00750 | Recruiting | Other |
| Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer | University of Rochester NCORP Research Base | URCC-16070 | Recruiting | Supportive Care/Symptom Management/PROs |
| Neuropsychological and Behavioral Testing in Younger Patients With Cancer | Children's Oncology Group | ALTE07C1 | Recruiting | Other |
| Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients | Alliance for Clinical Trials in Oncology | A222004 | Recruiting | Supportive Care/Symptom Management/PROs |
| Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program | Alliance for Clinical Trials in Oncology | A211901 | Recruiting | Cancer Prevention |
| S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer | SWOG Cancer Research Network | SWOG-S1501 | Recruiting | Supportive Care/Symptom Management/PROs |
| S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer | SWOG Cancer Research Network | SWOG-S1703 | Recruiting | Other |
| Study of Kidney Tumors in Younger Patients | Children's Oncology Group | AREN03B2 | Recruiting | Other |
| Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation | Alliance for Clinical Trials in Oncology | A211801 | Recruiting | Cancer Prevention |
| Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma | Children's Oncology Group | COG-ACCL1931 | Recruiting | Supportive Care/Symptom Management/PROs |
| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability | NRG Oncology | NRG-CC009 | Recruiting | Supportive Care/Symptom Management/PROs |
| Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial | Alliance for Clinical Trials in Oncology | A221801 | Not yet recruiting | Supportive Care/Symptom Management/PROs |
| Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy | University of Rochester NCORP Research Base | URCC-19075 | Recruiting | Supportive Care/Symptom Management/PROs |
| The National Myelodysplastic Syndromes (MDS) Study | National Heart, Lung, and Blood Institute (NHLBI) | ECOG-ACRIN-NHLBI-MDS | Recruiting | Other |
| To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring | ECOG-ACRIN Cancer Research Group | ECOG-ACRIN-EA8184 | Recruiting | Cancer Prevention |
| Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer | Children's Oncology Group | COG-ALTE1631 | Recruiting | Supportive Care/Symptom Management/PROs |
