A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
This clinical trial studies how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for individuals with BRCA1 mutations. Bilateral salpingectomy involves the surgical removal of fallopian tubes, and bilateral salpingo-oophorectomy involves the surgical removal of both the fallopian tubes and ovaries. This study may help doctors determine if the two surgical procedures are nearly the same for ovarian cancer risk reduction for women with BRCA1 mutations.
Research Base: NRG Oncology
NCT ID: NCT04251052
NCI Protocol Number: NRG-CC008
Status: Recruiting
For more information see ClinicalTrials.gov
Interventions
- Bilateral Salpingectomy
- Bilateral Salpingectomy with Oophorectomy
- Quality-of-Life Assessment
- Questionnaire Administration
- Biospecimen Collection
- Transvaginal Ultrasound
Condition
Ovarian Carcinoma
Trial Type
Cancer Prevention
See a list of participating sites on ClinicalTrials.gov